하악 제3대구치 발치 시 midazolam을 사용한 정맥진정법의 진정효과에 관한 임상적 연구

곽주희; 장진현; 김진우; 김명래; 김선종

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하악 제3대구치 발치 시 midazolam을 사용한 정맥진정법의 진정효과에 관한 임상적 연구
The clinical study on the sedative effect and recovery in patients undergoing intravenous conscious sedation with midazolam for mandibular third molars extraction

대한구강악안면외과학회지 2010년 36권 5호 p.408 ~ 412

곽주희, 장진현, 김진우, 김명래, 김선종,

소속 상세정보

곽주희 ( Kwak Ju-Hee ) - 이화여자대학교 목동병원 구강악안면외과
장진현 ( Jang Jin-Hyun ) - 이화여자대학교 의학전문대학원 구강악안면외과
김진우 ( Kim Jin-Woo ) - 이화여자대학교 목동병원 구강악안면외과
김명래 ( Kim Myung-Rae ) - 이화여자대학교 의학전문대학원 구강악안면외과
김선종 ( Kim Sun-Jong ) - 이화여자대학교 목동병원 구강악안면외과

KMID : 0355620100360050408

Abstract

Introduction: This study examined the depth of sedation and the usefulness of the monitoring tool in determining the level of sedation in patients undergoing third molars extraction under conscious sedation with midazolam.

Materials and Methods: Twenty two patients undergoing third molars extraction at the department of Oral and Maxillofacial surgery, Ewha Womans Mokdong Hospital from February 2010 to April 2010 were analyzed. All patients were classified as American Society of Anesthesiologist (ASA) class I and had no contraindications tosedation. The bispectral index was recorded continually during surgery using a bispectral monitor. The initial sedation was accomplished using a 3 mg bolus of midazolam followed by a 2 mg bolus of midazolam until the level of sedation, at which the patient’s eyes were closed or the subject was responsive only to loud or repeated calling of their name, was reached. All subjects were surveyed with a postoperative questionnaire to evaluate the level of sedation.

Results: The bispectral index (BIS) decreased approximately 5 minutes after midazolam administration, but increased at the local anesthesia injection and odontomy procedure. The amnestic effect was shown effectively in the early stages of surgery.

Conclusion: Conscious sedation with intravenous midazolam is effective in achieving the effect of anxiolysis, analgesia and amnesia. The BIS is an objective and useful means of assessing the depth of sedation.